1. DNA is composed of four types of bases (ATCG). What would be the implications if DNA structure had the four bases organized in clumps of four -- (ATCG)(ATCG)(ATCG)(ATCG)(ATCG)...... What is the evidence that this is not the case? (check out CSH: DNA/proteins (click "animation"), CSH: Watson/Crick)
   
   
2. Is ATGCGC equivalent to CGCGTA? Explain why/why not.
   
   
3. Is ATGCGC equivalent to GCGCAT? Explain why/why not.
   
   
4. Does RNA sequence match DNA sequence?
   
   
5. What is cDNA?
   
   
6. Illustrated is an alignment of the engrailed gene cDNA and genomic DNA sequences. [engrailed is a gene required for embryo development.] Explain the relationship between the sequences. Consider how this alignment of cDNA and genomic DNA sequences might have been obtained.
   
   
7. Could codons be 2 nucleotides long? (check out CSH: codons)
   
   
8. If you know a protein sequence, do you know its DNA sequence?
   
   
9. Is the protein sequence MASS equivalent to SSAM? Explain why/why not. (check out jkimbal link)
   
   
10. Does amino acid sequence determine protein structure and function?

Summarize at least three properties of RNA, DNA or protein sequences that have been considered in this session.